Apogée Deep Wrinkle Cream containing Apple Stem Cells proven in studies to reduce deep wrinkles and fine lines.
“Results showed a significant and visible decrease in wrinkle depth for 100% of the subjects”
Minimize fine lines and slow aging
Apple Stem Cells, a breakthrough for anti-aging products, help to slow the signs of aging by ensuring the longevity of healthy skin cells. Epigenetic factors and metabolites activate skin stem cells to help delay the aging of skin and begin skin rejuvenation. In clinical trials on the crow’s feet area of the eyes, they were found to reduce the depth of wrinkles by 15% in four weeks. The plant stem cells are incorporated into the Alphasomal® delivery system along with other active ingredients to effectively deliver them to the target area. What Are Stem Cells
Present in both plants and animals, stem cells contain specific epigenetic factors - cell information which is preserved through cell division - whose function is to maintain their ability to self-renew. In the body, adult stem cells maintain normal cell turnover and act as a repair system. In the skin, epidermal stem cells replenish and maintain the balance of cells and regenerate damaged tissue. Adult stem cells can only differentiate into their own or related types of cells; with age they decrease in number, and their ability to repair the skin becomes less efficient.Plant Stem Cells Protect Skin Stem Cells
In contrast to human stem cells, plant cells are totipotent, meaning every plant stem cell can regenerate any other cell. In cosmetics, plant stem cells have the capacity to boost human stem cells and therefore help them renew and regenerate cells to slow the aging process. Apple Stem Cells Delay Aging and Decrease Wrinkles
Apple Stem Cells were derived from the rare Swiss Uttwiler Spätlauber Apple, well-known for its excellent storability and thus its longevity potential. The Apple Stem Cells have an abundance of phytonutrients, proteins and long-living cells. Studies have demonstrated their age delaying and anti-wrinkle effects.ResultsMaintenance of Stem Cell Growth (Age Delaying Effect)* Graph of Stem Cell Growth
An in-vitro test was conducted on young skin stem cells with Apple Stem Cell Extract. The influence of the plant cells on skin stem cell growth was evaluated. Results showed that Apple Stem Cell Extract has a positive effect on growth, therefore delaying aging.Protection against UV Radiation
* Graph of Stem Cells against UV damage
An in-vitro test was conducted on young skin stem cells with Apple Stem Cell Extract. The protective effect against UV damage was evaluated by MTS assay, which measures the number of living cells and therefore the damage from UV radiation. Young skin cells were incubated with Apple Stem Cell Extract then exposed to UV radiation. Results showed the Apple Stem Cell Extract protects from UV damage, with only a 7% decrease in cells compared to a 42% decrease in cells.Anti-Wrinkle Effect on “Crow’s Feet”
* Photos of crows feet area
NotesApple Stem Cells
- The anti-wrinkle effect was evaluated in a study with 20 volunteers ages 37 to 64.
- Applied twice daily for 28 days to the crow’s feet. Wrinkle depth determined by PRIMOS.
- Results showed a significant and visible decrease in wrinkle depth for 100% of the subjects.
A Swiss Apple Variety with Incredible Properties Uttwiler Spätlauber is a variety of a Swiss apple that derives from a seedling planted in the middle of the 18th century. It was very famous for its excellent storability without shriveling. Today apple cultivars are selected to maximize crop yield and sweet flavor. Thus Uttwiler Spätlauber with its acid taste is now disappearing. Uttwiler Spätlauber is an endangered apple variety that was well-known for its excellent storability and thus its longevity potential. Uttwiler Spätlauber apples are rich in phytonutrients, proteins and long-living cells. This particular composition leads to incredible storability and longevity properties.
PhytoCellTec™ Malus Domestica is a liposomal preparation based on the stem cells of a rare Swiss apple.A Revolutionary Technology to Protect Skin Stem Cells Claims with PhytoCellTec™ Malus Domestica
- Protects longevity of skin stem cells
- Delays senescence of essential cells
- Combats chronological aging
- Preserves the youthful look and the vitality of your skin
Stem Cells and LongevityLongevity is related to specific cells called stem cells which have a unique growth characteristic.
These unspecialized (undifferentiated) cells can make identical copies of themselves as well as differentiate to become specialized cells.
Two basic types of stem cells are present in the human body:
Stem Cells in the Human Skin
- Embryonic stem cells found in blastocysts can grow and differentiate into one of the more than 220 different cell types which make up the human body.
- Adult stem cells located in some adult tissues can only differentiate into their own or related cell types. These cells act as a repair system for the body but also maintain the normal turnover of regenerative organs such as blood, skin or intestinal tissues.
Epidermal stem cells replenish and maintain the balance of cells within the skin tissue and regenerate tissue damages during injury. But with age, the number of skin stem cells decreases and their ability to repair the skin becomes less efficient.
Plant Stem Cells to Protect Skin Stem Cells
In contrast to human, plant cells are totipotent, meaning that every cell has the ability to regenerate new organs (leave, flower, seed…) or even the whole plant. Besides, all plant cells can dedifferentiate and become a stem cell. All stem cells, independently of their origin (plant, animal or human) contain specific epigenetic factors whose function is to maintain the self-renewal capacity of stem cells.